US Highway 78 / Interstate 22 accesses the Natchez Trace Parkway at milepost 263. This exit is located in Tupelo, Mississippi.

The map below shows the US Highway 78 access / exit to the Natchez Trace Parkway and also nearby attractions, towns and bed and breakfasts.

Tennessee - Alabama - Mississippi
Bicycle the Trace - Motorcycle the Trace - Festivals and Events