Tishomingo, a town in Tishomingo County, is located in northeast Mississippi about two miles north of the Natchez Trace Parkway.
Tishomingo is named after Chief Tishomingo of the Chickasaw tribe, who signed the Treaty of Pontotoc in 1832. He died on the infamous 'Trail of Tears'. His son, Iuka, is the namesake of the county seat of Tishomingo, County, Mississippi.
Tishomingo State Park, Mississippi's premier nature park, straddles the Natchez Trace Parkway.
The population of Tishomingo was 316 at the 2000 census.